Reasons as a thinking tool in philosophy play a central role in the discussions of this science. In the meantime, especially secondary philosophical reasons are of double importance in the direction of philosophical research and analysis. This is especially important in transcendental wisdom, which analyzes facts from the perspective of objective reality and not from the lens of the mind. In this regard, due to the importance of this discussion, Mulla Sadra has a special view on the second philosophical reason and has presented a different explanation from the famous opinion of his era in the second philosophical reason. Due to Mullah Sadra's distance from the point of view of being famous and liberating, some of his expressions in using the term "reasonable second", the late philosophers have been confused in understanding and presenting this debate, and some have even raised contradictory opinions. Therefore, in this article, while examining some of these opinions, we have investigated the nature and coordinates of the reasonable second philosophy in Mulla Sadra's point of view. One of the results of this discussion is to find the correct understanding of transcendental wisdom and especially the issues that are based on Mulla Sadra's basis in the reasonable second philosophical discussion on transcendental wisdom.